reference : Human Risk of Infection with Borrelia burgdorferi, the Lyme Disease Agent, in Eastern United States

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Bibliographic fields
reftype Journal Article
Abstract The geographic pattern of human risk for infection with Borrelia burgdorferi sensu stricto, the tick-borne pathogen that causes Lyme disease, was mapped for the eastern United States. The map is based on standardized field sampling in 304 sites of the density of Ixodes scapularis host-seeking nymphs infected with B. burgdorferi, which is closely associated with human infection risk. Risk factors for the presence and density of infected nymphs were used to model a continuous 8 km x 8 km resolution predictive surface of human risk, including confidence intervals for each pixel. Discontinuous Lyme disease risk foci were identified in the Northeast and upper Midwest, with a transitional zone including sites with uninfected I. scapularis populations. Given frequent under- and over-diagnoses of Lyme disease, this map could act as a tool to guide surveillance, control, and prevention efforts and act as a baseline for studies tracking the spread of infection.
Author Diuk-Wasser, M. A.; Hoen, A. G.; Cislo, P.; Brinkerhoff, R.; Hamer, S. A.; Rowland, M.; Cortinas, R.; Vourc'h, G.; Melton, F.; Hickling, G. J.; Tsao, J. I.; Bunikis, J.; Barbour, A. G.; Kitron, U.; Piesman, J.; Fish, D.
DOI 10.4269/ajtmh.2012.11-0395
Date Feb
ISSN 0002-9637
Issue 2
Journal The American Journal of Tropical Medicine and Hygiene
Keywords ixodes-scapularis acari; blacklegged tick acari; climate-based model; altitudinal gradient; forest fragmentation; habitat suitability; borne diseases; endemic area; sensu-lato; ixodidae
Language English
Notes 886PQ Times Cited:23 Cited References Count:56
Pages 320-327
Title Human Risk of Infection with Borrelia burgdorferi, the Lyme Disease Agent, in Eastern United States
Volume 86
Year 2012
Bibliographic identifiers
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_record_number 17733
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