reference : Residential proximity to nearest major roadway and cognitive function in community-dwelling seniors: Results from the MOBILIZE Boston Study

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Bibliographic fields
reftype Journal Article
Abstract OBJECTIVES: To evaluate the association between residential distance to nearest major roadway, as a marker of long-term exposure to traffic pollution, and cognitive function in older adults. DESIGN: Prospective cohort study with median follow-up of 16.8 months. SETTING: Community. PARTICIPANTS: Seven hundred sixty-five community-dwelling seniors. MEASUREMENTS: The Mini-Mental State Examination, Hopkins Verbal Learning Test-Revised (HVLT-R), Trail Making Test (TMT), category and letter fluency tests, and Clock-in-the-Box Test were administered during home visits on two occasions. The residential distance to the nearest major roadway was calculated, and generalized estimating equations were used to evaluate the association between performance on each test and residential distance to nearest major roadway, adjusting for participant demographics, education, socioeconomic status, and past medical history. RESULTS: Shorter distance to major roadway was associated with statistically significantly poorer performance on the immediate and delayed recall components of the HVLT-R, TMT Part B, TMT delta, and letter and category fluency tests. Generally, participants residing less than 100 m from a major roadway performed worst. Performance improved monotonically with increasing distance. CONCLUSION: In this cohort of community-dwelling older adults, residential proximity to a major roadway was associated with poorer performance on cognitive tests of verbal learning and memory, psychomotor speed, language, and executive functioning. If causal, these results add to the growing evidence that living near major roadways is associated with adverse health outcomes.
Author Wellenius, G. A.; Boyle, L. D.; Coull, B. A.; Milberg, W. P.; Gryparis, A.; Schwartz, J.; Mittleman, M. A.; Lipsitz, L. A.
DOI 10.1111/j.1532-5415.2012.04195.x
Date Nov
ISSN 0002-8614
Issue 11
Journal Journal of the American Geriatrics Society
Keywords Aged; *Air Pollution; Cognition/*physiology; Cohort Studies; Female; Humans; Male; Prospective Studies; *Residence Characteristics
Language eng
Notes 1532-5415 Wellenius, Gregory A Boyle, Luke D Coull, Brent A Milberg, William P Gryparis, Alexandros Schwartz, Joel Mittleman, Murray A Lipsitz, Lewis A AG004390/AG/NIA NIH HHS/United States AG25037/AG/NIA NIH HHS/United States ES000002/ES/NIEHS NIH HHS/United States ES009825/ES/NIEHS NIH HHS/United States ES015774/ES/NIEHS NIH HHS/United States K99 ES015774/ES/NIEHS NIH HHS/United States P01 AG004390/AG/NIA NIH HHS/United States P01 ES009825/ES/NIEHS NIH HHS/United States P30 ES000002/ES/NIEHS NIH HHS/United States R00 ES015774/ES/NIEHS NIH HHS/United States R37 AG025037/AG/NIA NIH HHS/United States Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. United States J Am Geriatr Soc. 2012 Nov;60(11):2075-80. doi: 10.1111/j.1532-5415.2012.04195.x. Epub 2012 Nov 5.
Pages 2075-2080
Title Residential proximity to nearest major roadway and cognitive function in community-dwelling seniors: Results from the MOBILIZE Boston Study
Volume 60
Year 2012
Bibliographic identifiers
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_record_number 18205
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